51本色

Generic medicines: an evaluation of the accuracy and accessibility of information available on the internet

Suzanne S Dunne1*, Niamh M Cummins1, Ailish Hannigan1,2, Bill Shannon1, Colum Dunne1,2 and Walter Cullen1,2

An evaluation of Medline published paediatric audits from 1966 to 1999

Aim: To evaluate the quality of paediatric audits from 1966 to 1999.
Methods: A Medline search was performed using the MeSH terms audit, child, paediatric (and pediatric).
Predefined core elements of audit were used as inclusion criteria for entry of an article into this study. These criteria were as follows: (1) an article deals with a healthcare topic; (2) a standard is predefined; (3) actual practice is evaluated; (4) actual practice is compared with the standard. The fifth criterion of audit, dissemination of information and reaudit, was not an inclusion criterion, as it was not used in the early years covered by this study. Empirical grading of standards was used.

Download PDF here

Sleep-Disordered Breathing Is Increased in Obese Adolescents with Craniopharyngioma Compared

Context: Retrospective studies suggest that adolescents with craniopharygnioma and hypothalamic obesity have increased sleep-disordered breathing (SDB).
Objectives: The objectives of this study were to compare the prevalence of SDB in adolescents with craniopharyngioma-related obesity compared with body mass index (BMI)-matched controls and to explore possible relationships between SDB, insulin resistance, and adipocytokines.
Design: This was a cross-sectional study of obese craniopharyngioma and obese control adolescents.

Download the pdf here

Identification of an autoantigen demonstrates a link between interstitial lung disease and a defect in central tolerance

Interstitial lung disease (ILD) is a common manifestation of systemic autoimmunity characterized by progressive inflammation or scarring of the lungs. Patients who develop these complications can exhibit significantly impaired gas exchange that may result in hypoxemia, pulmonary hypertension and even death.

Download PDF here

The Impact of Telemedicine Interventions Involving Routine Transmission of Blood Glucose Data with Clinician Feedback on Metabolic Control in Youth with Type 1 Diabetes

Our objective was to determine the impact of telemedicine (TM) interventions on the management of type 1 diabetes (T1DM) in youth. We performed a systematic review of randomized trials that evaluated TM interventions involving transmission of blood glucose data followed by unsolicited scheduled clinician feedback.

Download PDF here